Recursive partitioning analysis of prognostic variables in newly diagnosed anaplastic oligodendroglial tumors
نویسندگان
چکیده
منابع مشابه
Recursive partitioning analysis of prognostic variables in newly diagnosed anaplastic oligodendroglial tumors.
BACKGROUND Anaplastic oligodendroglial tumors are rare, and median survival varies widely. Analysis of 1p19q deletion is performed commonly and is an important prognostic factor. However, age and other clinical variables also carry prognostic value, and it is unclear how to incorporate them into clinical decision making or to combine them for prognostication. METHODS We compiled a retrospecti...
متن کاملStratification according to recursive partitioning analysis predicts outcome in newly diagnosed glioblastomas
Glioblastoma accounts for more than half of diffuse gliomas. The prognosis of patients with glioblastoma remains poor despite comprehensive and intensive treatments. Furthermore, the clinical significance of molecular parameters and routinely available clinical variables for the prognosis prediction of glioblastomas remains limited. The authors describe a novel model may help in prognosis predi...
متن کاملAnaplastic oligodendroglial tumors: a tale of two trials.
The treatment of patients with anaplastic gliomas with an oligodendroglial component, either pure oligodendroglioma or mixed oligoastrocytoma, remains controversial. In the early 1990s, it was recognized that some patients with these tumors demonstrated dramatic responses to systemic chemotherapy regimens, particularly the combination of procarbazine, lomustine, and vincristine (PCV), whereas p...
متن کاملNew treatment paradigm for patients with anaplastic oligodendroglial tumors.
Oligodendrogliomas are uncommon tumors in neurooncology that represent about 5% of primary brain malignancies. Their high sensitivity to radiotherapy and chemotherapy was observed a long time ago. Nonetheless, the evidence-based proof of the significantly longer survival in patients with oligodendrogliomas treated with combined chemotherapy and radiotherapy in comparison to radiotherapy-alone d...
متن کاملMolecular prognostic factors of anaplastic oligodendroglial tumors and its relationship: a single institutional review of 77 patients from China.
The increased chemosensitivity of oligodendroglial tumors has been associated with loss of heterozygosity (LOH) on chromosomes 1p and 19q. Other clinical and molecular factors have also been identified as being prognostic and predictive for treatment outcome. Seventy-seven patients with anaplastic oligodendroglioma (AO) or anaplastic oligoastrocytoma (AOA), treated in Beijing Tiantan Hospital f...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Neuro-Oncology
سال: 2014
ISSN: 1522-8517,1523-5866
DOI: 10.1093/neuonc/nou083